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however, dedicated cardiovascular outcome trial (CVOT) data have not yet been published, and cardiovascular benefit has not been demonstrated Phase 3 trials are ongoing
Previous concerns regarding an association between GLP1RAs and pancreatic cancer have not been confirmed by data from epidemiological studies or randomized trials
Image Credit: zimmytws / Shutterstock A recent review article published in the Journal of Clinical Investigation summarized the adverse effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual incretin receptor agonists such as tirzepatide
HIF-1-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia
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